Description

Buy ABT-199 online

ABT-199 (GDC-0199) is Bcl-2-selective inhibitor with Ki of <0.01 nM, >4800-fold more selective versus Bcl-xL and Bcl-w and no activity to Mcl-1.Buy ABT-199 online

ABT-199 is potent and selective inhibitor of B-cell lymphoma-2 (BCL-2) family proteins, currently in clinical trials ABT-199 inhibits the growth of BCL-2-dependent tumors in vivo and spares human platelets

Single dose of ABT-199 in three patients with refractory chronic lymphocytic leukemia resulted in tumor lysis within 24 h

Additional information

CAS Number

1257044-40-8

Compound purity

99%

Formula

C23H29FN2O • HCl

Appearance

White Powder

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